Topical anaesthesia for needle-related pain in newborn infants

Acute Pain Management in Newborn Infants

Clinicians balance the immediate risks and benefi ts of analgesia in infancy, but they also consider the long-term effects of repetitive acute pain against those of prolonged analgesic therapy on brain development. This issue of Pain: Clinical Updates summarizes the current evidence regarding acute pain management in newborns. In 2006, the American Academy of Pediatrics and the Canadian Pediatr...

Ketamine for procedural pain relief in newborn infants.

AIM To assess the suitability of ketamine for relief of pain caused by tracheal suction during ventilator treatment in newborn infants. STUDY DESIGN In a randomised, double blind, cross over trial, 16 newborn infants received placebo or 0.5, 1, or 2 mg/kg ketamine as two minute infusions in random order five minutes before four separate endotracheal suctions, with intervals of at least 12 hou...

Needle-Related Procedural Pain in Pediatric Patients

Topical anaesthesia for children's lacerations.

Objective-To compare the anaesthetic properties of conventional intradermal 1% plain lignocaine with a topical gel preparation of adrenaline (1:2000) and cocaine (4-7%) for use in treatment of children's lacerations. Methods-Children aged 3-16 years with lacerations (not of the digits or mucous membranes) were consecutively assigned to receive either adrenaline and cocaine (AC) or lignocaine. P...

Does topical amethocaine gel reduce the pain of venepuncture in newborn infants? A randomised double blind controlled trial.

BACKGROUND Topical amethocaine provides effective pain relief during venepuncture in children, and has been shown to have a local anaesthetic action in the newborn. AIM To investigate the effect of topical amethocaine on the pain of venepuncture in the newborn. DESIGN Randomised double blind placebo controlled trial. SUBJECTS Forty newborn infants, gestation 27-41 weeks (median 33), age 2...